Diabetes is manageable, but it takes an expert team to provide individualized care to live well with this lifelong disease. While many live well with the help of diabetes management, the University of Minnesota is actively engaged in world-class investigation focused on the prevention and cure of diabetes and its complications. Endocrinology. Apr 26, 2010 · Congenital adrenal hyperplasia (CAH), most commonly due to 21-hydroxylase deficiency (21OHD), has been studied by pediatric endocrinologists for decades. Advances in the care of these patients have enabled many of these children to reach adulthood. In contrast to the course and management of the disease in childhood, little is known about CAH in adults.Cited by: 10.
Glucocorticoids (“steroids”) have only been used to treat CAH for the last 50 years or so. While we have gained considerable knowledge and expertise about the treatment of CAH in children, there is much less information about the treatment adults with CAH. Optimal treatment for the adult continues to challenge the healthcare community. CAH Adult Study Executive. Congenital Adrenal Hyperplasia (CAH), one of the most common inherited diseases that affects 1:14,200 live births. It is the result of a genetic defect in one of the enzymes (typically 21-hydroxylase) required for cortisol biosynthesis, leading to reduced levels of cortisol and aldosterone, increased ACTH concentrations and consequently increased adrenal androgen.
She is also the scientific advisor to the Minnesota Department of Health CAH Newborn Screening Program. Dr. Sarafoglou is lead endocrinologist of the CAH/DSD workgroup of the Region 4 Genetics Collaborative, a consortium of hospitals and newborn screening programs from seven Midwest states.